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 | WellbutrinŽ is an antidepressant that works by affecting two chemicals in the brain that are believed to help regulate your mood (dopamine and norepinephrine). SR = Sustained Release
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Wellbutrin SR
Common Brand Name(s)
Wellbutrin SR (Sustained Release) Tablets
Uses
Wellbutrin is a pharmaceutical prescription antidepressant
which acts directly on the brain and other nerve cells.
It is also used to treat ADHD (Attention Deficit Disorder),
Bipolar depression, chronic fatigue syndrome, cocaine
addiction, nicotine addiction, and lower back pain. Also,
aids in quitting smoking (identical to Zyban). It is chemically
unrelated to tricyclic, tetracyclic, selective serotonin
re-uptake inhibitor, or other known antidepressant agents.
How to Use
This medication may be taken with food if stomach upset
occurs. Take doses at regularly scheduled times each day.
Do not take more or less medication than prescribed and
follow your doctor's instructions carefully. Taking more
than the recommended dose of bupropion will increase your
risk of having a seizure. Do not stop taking this medication
without notifying your doctor. Since this drug may cause
sleeplessness at first, it is best not to take this near
bedtime. It may take 4 weeks or more before the full effects
of this medication are noticed.
Side Effects
This medication is generally well tolerated. Dry mouth,
headache, increased sweating, nausea/vomiting, constipation,
anxiety, fatigue and blurred vision may occur. If these
effects persist or worsen, notify your doctor. Report
promptly: unusual weight loss or gain, palpitations, agitation,
trouble sleeping. Unlikely but report promptly: tremor,
dizziness, fainting, mood changes, slowed movements, difficulty
urinating, decreased sex drive, drowsiness. Very unlikely
but report promptly: seizures, mental problems, fever,
muscle aches, yellowing of the eyes or skin. In the unlikely
event you have an allergic reaction to this drug, seek
medical attention immediately. Symptoms may include trouble
breathing, rash, itching, swelling, or severe dizziness.
If you notice other effects not listed above, contact
your doctor or pharmacist.
Precautions
Before taking bupropion, tell your doctor if you have:
history of seizures or head injury or brain tumor, heart
disease, liver or kidney disease, eating disorder, diabetes,
alcohol dependence, any allergies, the intent to quit
smoking. Because of the possibility this drug will make
you dizzy and affect coordination, do not drive or operate
machinery until you get used to the drug's effects. Limit
or avoid consumption of alcoholic beverages; alcohol can
increase your risk of seizures. Chronic alcohol users
who suddenly stop the intake of alcohol while taking bupropion
may increase the risk of having seizures. Suddenly stopping
certain tranquilizers (e.g., diazepam, chlordiazepoxide)
is not recommended because doing so may increase the risk
of having seizures. Elderly patients may be more sensitive
to the effects of this drug. Tell your doctor if you are
pregnant or plan to become pregnant before taking this
drug. This drug passes into breast milk. Because of the
potential risk to the infant, breast-feeding while using
this drug is not recommended. Consult your doctor before
breast-feeding.
Drug Interactions
Before taking bupropion tell your doctor of all nonprescription
and prescription medications you may use especially: MAO
inhibitors (e.g., isocarboxazid, phenelzine, tranylcypromine,
pargyline, selegiline, linezolid, furazolidone), levodopa,
ritonavir, corticosteroids (e.g. prednisone), sedatives,
adrenaline-like stimulants (e.g., ephedrine), products
containing nicotine (e.g., patches or gum). Also report
use of drugs which might increase seizure risk (decrease
seizure threshold) such as: phenothiazines (e.g., chlorpromazine),
tricyclic antidepressants (e.g., amitriptyline), isoniazid
(INH), theophylline. Excess caffeine intake can increase
the chance of seizures with this drug. Check all nonprescription/prescription
drug labels for caffeine. Consult your doctor or pharmacist.
A certain product used to help quit smoking contains bupropion.
Do not take that product while using this one. Do not
start or stop any medicine without doctor or pharmacist
approval.
Overdose
If overdose is suspected, contact your local poison control
center or emergency room immediately. Symptoms of overdose
may include seizures, hallucinations, rapid heart rate,
and loss of consciousness.
Notes
Do not allow anyone else to take this medication.
Missed Dose
Take any missed dose as soon as possible but not if it
is within 4 hours of the next dose. If it is time for
the next dose, skip the missed dose and resume your regular
schedule. Do not "double-up" the dose.
Storage
Store at room temperature and keep away from moisture
and sunlight. Do not store in the bathroom.
